Structural Biology

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Our research is focused on the structure-dynamics-function correlation of globular and membrane proteins.

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ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism.

Submitted by Administrator on February 14, 2012 - 17:00

Sengupta, S.; Ganguly, A.; Roy, A.; Bosedasgupta, S.; D'Annessa, I.; Desideri, A.; Majumder, H. K. ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism. Nucleic acids research 2011, 39, 3295-309.

Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin.

Submitted by Administrator on February 13, 2012 - 00:04

D'Annessa, I.; Tesauro, C.; Fiorani, P.; Chillemi, G.; Castelli, S.; Vassallo, O.; Capranico, G.; Desideri, A. Role of Flexibility in Protein-DNA-Drug Recognition: The Case of Asp677Gly-Val703Ile Topoisomerase Mutant Hypersensitive to Camptothecin. Journal of amino acids 2012, 2012, 206083.

Structure of nanoscale truncated octahedral DNA cages: variation of single-stranded linker regions and influence on assembly yields.

Submitted by Administrator on January 19, 2012 - 13:49

Oliveira, C. L. P.; Juul, S.; Jørgensen, H. L.; Knudsen, B.; Tordrup, D.; Oteri, F.; Falconi, M.; Koch, J.; Desideri, A.; Pedersen, J. S.; Andersen, F. F.; Knudsen, B. R. Structure of nanoscale truncated octahedral DNA cages: variation of single-stranded linker regions and influence on assembly yields. ACS nano 2010, 4, 1367-76.

Deciphering the structural properties that confer stability to a DNA nanocage.

Submitted by Administrator on January 19, 2012 - 13:49

Falconi, M.; Oteri, F.; Chillemi, G.; Andersen, F. F.; Tordrup, D.; Oliveira, C. L. P.; Pedersen, J. S.; Knudsen, B. R.; Desideri, A. Deciphering the structural properties that confer stability to a DNA nanocage. ACS nano 2009, 3, 1813-22.

Read more about Deciphering the structural properties that confer stability to a DNA nanocage.
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